IS NEMBUTAL A DEPRESSANT - AN OVERVIEW

pentobarbital will lower the level or effect of fentanyl by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead to a minimize in fentanyl plasma concentrations, deficiency of efficacy or, potentially, progress of a withdrawal syndrome inside a patient